THROMBOSIS AND HEMOSTASIS Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study
نویسندگان
چکیده
Departments of 1Clinical Cardiology and 2Rheumatology, University Hospital, Padova, Italy; 3Department of Angiology and Blood Coagulation Marino Golinelli, University Hospital, Bologna, Italy; 4District Hospital, Cremona, Italy; 5Internal and Vascular Medicine, University Hospital, Perugia, Italy; 6Internal Medicine, University Hospital, Cagliari, Italy; 7Transfusion Medicine, District Hospital, Merate, Italy; and 8Angiology Unit, Department of Internal Medicine, Santa Maria Nuova Hospital, Reggio Emilia, Italy
منابع مشابه
Laboratory Diagnostics of Antiphospholipid Syndrome.
Diagnosis of antiphospholipid syndrome (APS) lies in the recognition of antiphospholipid antibodies (aPL). As standardization of tests for the detection of aPL is far from being optimal and reference material is not available, inappropriate diagnoses of APS are not unusual. In the last few years, the concept of triple test positivity has emerged as a useful tool to identify patients with APS. C...
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The antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies in plasma of patients with thromboembolic complications. A major problem in defining the syndrome is that serologic assays to detect antiphospholipid antibodies have a low specificity. We recently published a method that specifically detects lupus anticoagulant (LAC) caused by anti– 2-glycoprotein I an...
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To assess the clinical significance of lupus anticoagulants (LAs) and antiphospholipid antibodies (aPLs) toward thrombosis and abortions, we measured them in 112 patients whose samples were available at enrollment in the warfarin in the antiphospholipid syndrome (WAPS) study. Enzyme-linked immunosorbent assay (ELISA) and coagulation test values in the highest and lowest tertiles were compared. ...
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1Department of Hematology, University Hospital, Nîmes, France; 2Research Team EA2992, Dysfonction des Interfaces Vasculaires, University of Montpellier 1, Nîmes, France; 3Laboratory of Hematology, Faculty of Pharmacy and Biological Sciences, Montpellier 1 University, Montpellier, France; and 4Departement of Biostatistics, Epidemiology and Medical Information, 5Department of Vascular Medicine, 6...
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